Player is loading...

Embed

Copy embed code

Transcriptions

Note: this content has been automatically generated.
00:00:00
production of and fourteen patients great to be here and talk to you'll
00:00:05
see some of the themes the the the um so it
00:00:09
wonderful here is that we will it be occurring in my dog
00:00:15
but to start that i really like to show a a slide that
00:00:20
which reminds us that you know that one can sink about the
00:00:23
human and this the mike about those neglected or done that
00:00:29
well it has made me sit and many says imagine rolling fell some disease and that
00:00:36
i used it that that that for chronic diseases with this live which goes one failed things seniors that
00:00:43
oh a couple of us go this is an n. yeah there's a the the note
00:00:48
amanda diseases so that the slide is get would get longer and longer so it just a bit yep but
00:00:55
but that an important that sink to remember also
00:01:00
is that chronic diseases are steadily increasing in that's so as
00:01:04
countries and that there is no prevention and knock you
00:01:09
so it is a major health problem uh
00:01:15
oh of course but attention of b. is currently diseases could impact that because greatly
00:01:22
and the simple way of viewing prevention is saying about that two components is the
00:01:26
direction and this guy with the asians not enough to detect there is
00:01:31
we also have to do something about it and they just want to call it that
00:01:36
the microphone for an on the risk of chronic disease can it be a target
00:01:40
for inter dimension ensure that you recognise some of the themes that we um
00:01:44
it it is but if that that that the other lacking
00:01:48
really tools to assess the the microphone where enough
00:01:54
how to assess the state of these neglected organ each and every individual
00:01:59
environment that could consortium we always do but that that challenge it
00:02:05
it by saying okay we should probably start by describing what's the status of
00:02:12
what's it uh uh well got to belong the other
00:02:15
human genome enough but collectively we can okay in
00:02:20
our uh uh intestinal tract and and try to find out what is the other gene on it
00:02:27
each and every individual and for that we developed yep approach to do it uh
00:02:33
maim quantitative methods are not mix of what this quantitative nitrogen onyx
00:02:37
quantitative methods er non x. ray start from schools samples and go all the way to
00:02:46
predictive models and the indication of how to go about it and how
00:02:50
they do that we have developed methods which make it seem to
00:02:55
to collect it stool samples that can now be that that can now
00:02:59
be done patients clones we could develop quenching liquid so it
00:03:04
composition of my problem is not about that for a leak but it is still samples
00:03:10
can then they send send a mail from the patients cons to the lab
00:03:16
and when the lab receives it and all the n. a. is extracted
00:03:21
so on that and that captures of calls all the genes that individual carriers
00:03:27
to find out what the the genes in the sequence a lot generate
00:03:32
many many sequences of the fifteen you don't sequences which capture presence
00:03:36
on the buttons of the jeans they're short sequences and a button for
00:03:39
not good on their own so we basically use them to
00:03:45
ma on direct ranging caught the which contains all the g. is that we have ever found
00:03:52
mark infinitely ma non um because the shot sequence to this reference
00:03:57
jane caught all the county jane so they get jean profiles
00:04:01
for many individuals and millions of jeans and the the
00:04:04
the ladies provost document data in from there they
00:04:09
identify the unthinkable whereas the oven has to be from others and in
00:04:14
principle it looks quite simple and keep these but there is it
00:04:19
critique of point basic needs to be standardised because it if it's a collection
00:04:25
is out of storage or sample processing does not done quite i than
00:04:30
it's very difficult to correlate sings between difference that isn't that has i sink impacted the field to sun
00:04:37
the the if not the most clad into different gene catalogue
00:04:42
is it the cut above ten million genes yeah that has just been published a few months ago
00:04:51
the big contribution from b. g. i. integrate to happen john
00:04:56
it does he meant if you expand on that that like that later on
00:05:01
about twelve hundred individuals that that that uh
00:05:05
started and caught is it one of the messages from here remember the first catalogue huh
00:05:13
the obvious that got this major cover the push on was one hundred twenty four individuals ten
00:05:19
times more than compared to him you and you know one of the main messages is
00:05:25
well the thing is that the common to many individuals up to don't think is very much
00:05:30
any long it's like a common buttons that jane is that right there is something about
00:05:37
at least five percent individuals well that maybe between jen from millions of these we have seen them
00:05:44
now what's intriguing of course is that and a jeans present in the if you will be the
00:05:48
just a link isn't maybe the quilt she did that to that notion that we are also
00:05:53
different but maybe also part of it is that some of the microbes that live
00:05:58
in our budget i don't to reside there but other transit in there
00:06:04
be as it may be seeing that this common jeans with the most informative for that
00:06:13
common diseases chronic diseases that we would like to that
00:06:21
but beyond ten even jeans i also wanted to cluster the genes in
00:06:27
classes of gene once they confound and we we the that that
00:06:35
i won't go into details of the of the procedure which really goes it
00:06:41
looking at the core abundance of genes in different individuals
00:06:45
jeez which have same abundance it was different individuals they want to the same speech
00:06:50
what have we found we had found if we look at the frequency of
00:06:56
objects class there's even foreign which caught my page among units here that
00:07:02
so am i allowed to have many genes and
00:07:05
they really the present species bacterial species which
00:07:10
are call methods are not mixed finishes we could describe it's also paper that came
00:07:15
out there that these these here we discuss it the it we call this method amongst dishes
00:07:21
eighty five percent of them that previously i'm no so
00:07:25
quinn only the gnome speeches that i thought it was jean answered being used to cannot there's back about
00:07:32
lines cannot present on the t. v. percent of all that is in there but that not only does a large
00:07:40
species and is that also smaller you wanted to chat
00:07:44
say less than about seven hundred genes maybe it's
00:07:48
i mean is it around that maybe fifty genes and they correspond to pay
00:07:54
just by the spasms crisper elements that sell the stuff i think
00:08:01
and really detailed description of this whole michael brown they can
00:08:06
consist construct these into action networks you can set
00:08:12
if age it is not a bacterium on which the page see it's
00:08:16
so they know about these relations and that this is a zoom on one part of this network
00:08:22
this particular methods among species we see some pages
00:08:27
which you attack we see an annuity element
00:08:31
and for and is even even the element is present in some strange but not in dallas and
00:08:36
the stage will not that back to the look at the data that a presentation of
00:08:40
what is going on and we can categorise oh that but neglected organ
00:08:46
we can assess microbe around and each and every individual to and and this and then the the the
00:08:53
and you can you can even think about this quantitative
00:08:57
methods enormous approach as a part of my possible
00:09:00
microscopic scanned the neglected organ waste away from i'm twenty one level
00:09:05
folks first microscope it some time ago yet another that person
00:09:14
so what can we then do i use state what we can do it in
00:09:20
the following sites get into a few examples we can do that last
00:09:27
a paper published a couple of months ago on lever settles
00:09:34
done in collaboration rate the other part is
00:09:38
that that generation university in fine huh
00:09:43
because i've got about about almost two hundred fifty people
00:09:49
patience reverse arouses that most in different ways controls people who come for
00:09:54
a a forecast check we speak out caught in a discover
00:10:00
to find out species that deeper in shape and show them
00:10:05
in in a few moments patience and as individuals
00:10:10
and train the algorithm which these diagnoses
00:10:15
with about ninety four percent accuracy
00:10:19
between patients and controls and i used the remainder of a corporate
00:10:23
which was never ever used to train the ability to get
00:10:26
exactly the same type of a precision we only seven
00:10:32
seven species we've had these accuracy of diagnostics so
00:10:38
many times people ask layout quite at the compound is we have a leaning they could
00:10:45
that confounded it as confound their disease state was we can
00:10:51
it is it accurately that the most compensate it patients and the
00:10:57
compensated patients may have also eliminated the effect of medication
00:11:04
anti virus that that bothers about the problem about if we because because we can distinguish
00:11:10
that most people use respective whether they take does that so not so hot
00:11:18
today
00:11:20
gotten standard for all the the solos that causes biopsy that season in the is it better
00:11:28
and you can't like it's not simple getting replacing with it the non invasive method school no it's
00:11:37
so we can diagnose with high accuracy
00:11:41
but it can also say something about beyond that that no since we can say something about the status
00:11:46
of the patients that i take a few minutes to you mormons guide used to these colourful slide
00:11:57
so first we haven't organised i'll call what this is a discovery by this
00:12:02
is about the ocean but into as individuals and leave us those patients
00:12:08
and then the the present twenty a species matter now is
00:12:14
speech is that that initiative uh solos and the
00:12:18
uh so the method journalist dishes that the marriage has individuals
00:12:23
but these boxes each of the boxes ideally the presence
00:12:27
see the genes of the species and there's a couple called for the
00:12:32
for the uh uh uh uh this uh presentation so ha
00:12:37
the problem here is one individual ninety eight a. b. c. and so on and each
00:12:44
line each role is a gene and fifty genes that this late so can easily see
00:12:51
that these twenty eight stages at present mostly in
00:12:55
leave aside those patients both in the discovery and evaluation corporate but these dishes
00:13:02
i dunno us from the patients that another there that typical for yes individuals there's it yet but
00:13:10
now we have also or that the other sellers patients here
00:13:16
in terms of the abundance of these dishes for in in the database
00:13:23
and what we see when we compare the quartet let's say
00:13:27
patients whichever least of this this is your patients which it most of the stages
00:13:33
the the legal schools are not lost all people
00:13:36
who have high load of leaves those pages
00:13:41
then for people who have low logo that so they can not
00:13:45
only diagonals patients we can also say how sick very ah
00:13:52
so what's going going to be the there's a massive change of michael by um in a way but so was
00:14:00
one parameter which i touch up on a more but later they haven't lost
00:14:08
that is significantly regions of that michael by on both
00:14:12
in discovery caught user l. c. and patience
00:14:19
these two species it that they're shown you in some patients it
00:14:23
does end up to forty percent of the microphone it's not
00:14:27
a small change it's a field chain button has individually we don't think find them but
00:14:34
a lot of people here and i guess it could you please number of these innovators and
00:14:39
i think they should go back and be that most because maybe they are actually seek
00:14:46
now
00:14:48
when you look at the species data lost from the patients which are in the region has individually
00:14:55
that the because the because it it's the issues that you find in the got
00:15:00
for most of them they don't have that so long or at niche assignment
00:15:08
for those that we have a well i come from the got but this the issues that we find in the patients
00:15:15
good mentality is actually or else the shoes there is an
00:15:19
invasion pass location of the michael brown from the mouse
00:15:23
two but that so we'll leave it normally we didn't mealy grounds of
00:15:28
that the yeah no mask it's not good for you to have found about
00:15:31
two hundred grants in your that and when you cannot live there
00:15:37
biochemical metabolic potential big lucy there they would impact
00:15:44
among at the base mind that is there is that right and these are the actually
00:15:50
factors that impact it hypnotic and said that and i thought i think so
00:15:58
there you have it it's kind of toxic might come down and it's interesting that
00:16:04
in the literature you can find association of santa hats
00:16:09
and the higher mel scores which are used to
00:16:13
about what's the use of the reverse sellers
00:16:20
okay we can perhaps we can say something about that patients
00:16:25
follow trying to be take that is at which these patients uh
00:16:31
oh it was thought it'd published last year high and low income
00:16:36
you some people can login car stamp you have hygiene come
00:16:43
they happened to be seated and you call me among
00:16:47
the and teletext coding count gauges that mostly
00:16:50
back there it is and they're not that hard in com mostly not couples and the like
00:16:56
if i look sick this species that they haven't eugene some or
00:17:00
it also ordered by the gene number login prompt
00:17:05
individuals ah you mean like species which
00:17:08
are known or suspected to be brought inflammatory and hide in crime in the us
00:17:14
they're talking with the shoes which are typically an right and one there
00:17:19
and of course this is being used by all these big difference
00:17:23
in amman method among species which of course the majority
00:17:28
but of course we just absolutely stipend is the login crank individuals and
00:17:33
it's one person youthful one there's something for one two three four
00:17:42
at least they have less fancy metabolic an inflammatory traits and that
00:17:48
does it gives some of the details about it but it
00:17:53
what it's really say see that login concretely they
00:17:56
just at e. p. is that people that the increase in doing the resistance this leading yeah and information
00:18:04
and we have not done longitudinal starts to say ah ha this
00:18:10
is that east but we talk to clinicians inclusion nations
00:18:13
tell us that they know from clinical studies that people who work these two eight is to not right
00:18:20
ah it had basic attacked about it is kind of
00:18:23
us go these about problems and pencil not only
00:18:28
the clinical picture of this people say is that there had is
00:18:32
but also all the time over past nine he said he had an egg whites
00:18:39
little old gene clark all these people have pulled down significantly morally
00:18:45
and i didn't want people to not only gamblers all
00:18:48
that getting more and more into that that direction
00:18:54
so the analyst there michael but i'm and found that people
00:18:59
who habit high levels of certain methods amongst the issues
00:19:04
pain less way all the time and that's it displayed phoebe image shine change
00:19:12
big a much more when they have low level of these speeches in file level of the speech is
00:19:19
could these have a protected or or we don't know what they are they don't have that so manic
00:19:24
assignment but they can place them kind of when you get it but
00:19:28
produces maybe just wander but it's not one of the important facets
00:19:33
of that not that not that it was absurd the ins and event and look
00:19:40
it french and a fine basically the same type of change
00:19:44
that these by motel at the distribution of individuals
00:19:49
hide income volume cow make to these bios saying that that and are not the call what was
00:19:56
lower smaller so the power was it's that that a lot
00:20:00
so we found only a species but popping out of this eighteen but also highly busting danish study
00:20:07
the train our algorithm to distinguish low and hygiene
00:20:12
con people on forty now nine range
00:20:15
six methadone long speeches could identify thanks to ninety five percent accuracy
00:20:20
and the same algorithm the same algorithm works as the out for banks
00:20:27
the rains
00:20:29
french we went to touch you can't that would that look at
00:20:34
lincoln centre spouses because see once again these an even
00:20:39
distribution the it's less clearly by mogul nineteen percent one out
00:20:43
of five that's what big selected them to be healthy
00:20:47
in this has a guy see see that these these keen on methadone long speeches and
00:20:51
they bias in distribution the same algorithm that button potential and the and the
00:20:58
a dangerous for that as well and that legal parameters go in the same
00:21:05
direction so we do see this huge difference in all of
00:21:09
them and and to try to put the microphone
00:21:13
the potential of michael but i'm in login kong individuals
00:21:18
let me see say this a good friend of ours i can man's yet is low
00:21:25
due to produce new production is a lot that is low bit about the room seemed to be
00:21:31
well and what this high l. p. f. producer tore inflammatory it guys so it'll sink bit
00:21:39
michael button in login count individuals is less fancy so that
00:21:46
we get this kind of meta analysis on about sixteen hundred people some people uh
00:21:53
yeah see and i have had encountered it hygiene count the uh
00:22:01
most of them about operational separate sodium content hide income
00:22:07
that danes looked at spain spain yeah says that i combat in the moment this tool
00:22:14
but when that one both to patients say all these types about it is nash
00:22:21
or i'd be beating up i'd be is that is the last but one day because that it this is kind of exception
00:22:28
and that it's into an interesting exception but in many of these diseases
00:22:33
this neglected organ seems to atrophy so how about these actual costs we
00:22:38
don't know but there is a real no logical see that
00:22:42
well by that that maybe some problem with it because all these
00:22:46
guys that analysts they didn't like the pipeline directly develop
00:22:52
so there are some differences for the other two and if you look at the project that imagine onyx
00:22:57
then one can distinguishing the two parts of the d. n. a. sequencing and
00:23:02
by informatics which we sink was rather standardised across this that is
00:23:07
but there are some differences sample collection processing these two says and we just don't know whether
00:23:14
it's an real loss on that part of the last in this court wasn't important is to establish
00:23:21
because it may using the standardisation his critical and we really need to look into it
00:23:31
so yes we can detect the sky
00:23:37
but read and we also need to alleviate can microphone be
00:23:41
a target for intervention in the sink about this
00:23:44
mike about that to be a should not as a package and which can saying it's not a
00:23:50
abel alliance it's kind of population change like you topic lakes
00:23:56
okay the the stroller micro by um and that
00:24:00
it be tempted to do that in michael b. is that it
00:24:05
forty nine all of it or bees french which are
00:24:10
following colour yes they could die for six weeks and maintenance that was six weeks
00:24:15
that was that and and responsibility of putting them on from your
00:24:18
subject yeah sure but i was caught the middle east
00:24:22
study the dietary intervention as i said was colonial as they did
00:24:28
hi propane law about that and the seven and the the the the fibre
00:24:36
what we observed of course is that all the metabolic that on it does improve that's
00:24:40
that that was expected but what we also also is that you
00:24:45
can login pond individuals these gene count land that it
00:24:51
was improve although not fully we also so that fight unity just people believe spun better
00:24:58
in addition of intervention so that's stratification between respond there's and non responders
00:25:07
another intervention in the contest so ideas we probably ought to
00:25:12
exit the chip we've just got published or not
00:25:17
probably august people eat that these are meant that meet meet but that's what's going on
00:25:22
the the able to fine and number of methadone long
00:25:26
speeches small number of nitrogen angst the feature
00:25:30
impacted greatly by pro that probably ought to consumption this method announced
00:25:35
dishes most of them had that you carry that aspect
00:25:41
what else we look at the models separately mode use but clearly increase in the microphone
00:25:48
and they also try to do that and that too comfy and that sort of
00:25:54
or observation by adding probably ought to think that i think the show got system
00:26:00
re supposed is likely to beauty conversion so yes
00:26:05
we sink we can impact in different ways michael but so
00:26:12
one of the messages his role might that wasn't the mad about lonely just mike about appears to be
00:26:17
less i'll second that now simply identify individuals at least
00:26:21
and interventions good can corrected and possibly alleviate
00:26:25
various countries could have major impact on public yes
00:26:30
just as a reminder chronic diseases you know that i frequent and costly
00:26:34
four point four percent of the population scientists some type true that it is
00:26:40
cost usually causes that you don't use this is the deficit of
00:26:44
social security in in france in the passage male of
00:26:48
the long euros here regularly politicians that that was something about
00:26:53
then it goes back to that so if we could
00:26:57
maybe hands chronic disease by systematic analysis and treatment of market mike about that
00:27:03
is that section of the allegation we could perhaps impact these things
00:27:08
but the question they often arises when people ask me regularly
00:27:13
so that's what i'm going to replace it directly east
00:27:16
change of microbial population causal consequence of chronic disease and
00:27:20
i think it's a question for a lazy mind
00:27:24
and i think that it is a car it meant that it would be
00:27:28
an email and question actually because i think the people replace the mines
00:27:34
forget that the data is it yet another after not the and it is it
00:27:39
up in my problem could contribute to the disease and there is the
00:27:43
likely you know single clothes for chronic disease and that you know it's the
00:27:48
missions that it's totally and fear last this stupid question ah okay
00:27:57
so let me give you some examples which i have presented how could my kingdom come cheated
00:28:04
to the disease do all region is that my problem may be less
00:28:08
has intel lower beautiful produces and that in the past that has
00:28:13
that abandoned one find out there is the issue that systemic information which clinicians stanley
00:28:19
is a facet of almost all it's not all chronic diseases
00:28:24
the at my other example is leave aside was
00:28:28
quit the sink it is got macro microphone maybe toxic by producing
00:28:34
factors which impact and sell it and said poppy
00:28:39
angelo doctors she these guys like even then it's okay
00:28:45
and it and they feel that this okay even ah an experiment an
00:28:49
intervention they feel better now we understand why they would feel that
00:28:55
so how could that place has a toxic michael but i'm
00:29:00
one thing happen but try it and like to present two scenarios
00:29:05
who one is what i call the shots i personally
00:29:09
and that i think is it could be the case in little region speak a cheaper but she got to be
00:29:17
here so i almost made a pathogen interaction infections full of buttons
00:29:22
closing um what is the inflammation of sequence that in information in interested
00:29:31
i think that is all you we know that this michael biologists information to select
00:29:38
for species which dollar information which can be off if i
00:29:42
draw species which kennedy or there'd be a night
00:29:45
so that's your brought about the area which in here than
00:29:49
produce lots of l. p. s. and stimulate from all
00:29:53
information so here have aside to information say settler speeches which promote information then you get this
00:30:00
here's a usual second which we need to break his opera inflammatory my
00:30:05
problem which predisposed to add that it's chronic disease my second
00:30:09
scenario is loss of but here it's a it's a matter
00:30:12
of basing that these might may well happen in labour
00:30:17
said last but she can be virus infection in all about
00:30:21
that the obesity opinionated power right either sinks but that
00:30:27
we postulate leads to input by production and that has been established the dawn
00:30:34
discovery but as it is now the purples is a more the
00:30:38
but here is a little over and then this is all about the yeah and full blown pathogens it's also fine
00:30:44
can now get into these no leash and that at the end the
00:30:52
i think that ties all these motives which are not good for that so i think that
00:30:57
we should strive we still owe preserve health but modulate pink and if l. c.
00:31:04
toxic microphone and please don't nice understand icing that me understand the mechanism does
00:31:11
a beach we happen but please change the patent it's not called
00:31:16
or consequence its contribution and that type understand how it works and have the patience by
00:31:23
doing something about it and i think that the um also pleaded
00:31:27
for that but helping choose introduced my covenant public as well
00:31:33
as a few words about me page it more police
00:31:37
which was conceived by government by our government gay was nine million it nineteen
00:31:44
you don't you also the period to try to address these questions
00:31:50
may these technology available for academics medics industry tried and apple
00:31:56
my problem was things enjoyment has of course but also more than domestic animals that work for you know so you know
00:32:04
you know i mean cartons it use morse about animals as well and the number of
00:32:09
of applications so what is methadone up with platforms and the clinical interface
00:32:14
our clinical interface is because not prepared most people buy i
00:32:18
can program it thirteen claim all uh yeah it has
00:32:23
one of the because hospitals in europe so out is the patients in clinical studies
00:32:29
another of pop on this is cut within the rest of the on health says
00:32:34
for for a pickle and societal issues because we do lose sync because people can
00:32:39
have a great impact on the side and you'd rather be advise and help
00:32:45
in that the cheaper happens that operate it for buttons about operated by it in there
00:32:51
one has to do with samples by bond procedures automation standardisation
00:32:58
our objective is to have about bank of over one million stool samples and the just
00:33:03
a very small pilot study 'cause think about four hundred million also of europeans
00:33:09
around here we and we of course are integrated with bother bunks that
00:33:14
in um in france it one of the big hurdles is that the
00:33:21
data analysis that and they can standardise that best allies that's so
00:33:26
it works quite quite well quite big hate that but it because he
00:33:30
knows that it's not just the ones i've despite agenda about four
00:33:33
point five data bytes of of they can pick and have that in in base although
00:33:39
the best of this to go now is take a little longer
00:33:42
we also have a functional nitrogen angst local was the mechanism
00:33:47
what is responsible for the the elegance is we don't know
00:33:49
local culture all these microorganisms and waiting there would be
00:33:53
alone can output caught caught the but some of them we known their the enemy weeklong like for the
00:34:01
katie forty jeans inequalities have a library which contains about search team
00:34:06
mealy on jeans and then we can screen the activities
00:34:11
of the jeans clad in these libraries by putting them out but otherwise it's in contact
00:34:16
read to you kind of cell lines we have about sixteen screens immunity probably punishment
00:34:22
populism and others that i've been to but and number about acted clones
00:34:27
that are good candidates to go further saying that uh the out of
00:34:31
the path engaged in methadone onyx with the number of visible
00:34:35
papers but it's really planned for scientists of course and it it it's good to see
00:34:42
it that another friend so that you don't know giles a little so it's it's kind of an but that
00:34:49
it's not enough because to not the so side it you have
00:34:53
to engage industry and that we are doing that actively
00:34:58
but i found we had around reach as a as a mission
00:35:03
describe here and it weeks back to have all these but the
00:35:08
of each needs assessment kate by the end of the year
00:35:11
basically which should have been going for that so
00:35:17
i do think that sure my my problem hasn't see attention of into hot topic as
00:35:24
that was six broadcast expansion monitoring target for modulation to improve
00:35:29
has of course that's what we would like to do
00:35:32
and they sing that it could have shift the focus of might see which is mainly cute native to paint
00:35:38
to costly prevented them tomorrow invest say not only
00:35:44
until the resources but also and documents seven
00:35:49
so i just need to acknowledge its many good friends and
00:35:54
the us you see what some of them around
00:35:57
here like this guy may have seen before and this guy unseemly prude with me a little while
00:36:03
michael obvious cup collaborators ought to be made that you
00:36:07
not only steam it without phone nothing would be
00:36:11
a a nice input fat happen that i'd love and that by the commanding
00:36:16
you to pay good cablevision michael by author so it's
00:36:20
h. s. these wonderful japanese garden rich and beautiful
00:36:25
and it is a very final slide i'd like to invite all of
00:36:28
you to the next day you don't inhuman microphone information from
00:36:33
an michael been hundreds you should have that makes the the unit

Share this talk: 


Conference Program

Introduction of the Session 1 : The Gut Microbiome: Facts and Figures
Josef Penninger, Institute of Molecular Biotechnology, Vienna
Oct. 23, 2014 · 9:07 a.m.
648 views
The role of commensal bacteria in the gut
Willem de Vos, Wageningen University, The Neterlands
Oct. 23, 2014 · 9:31 a.m.
568 views
Q&A : The role of commensal bacteria in the gut
Willem de Vos, Wageningen University, The Neterlands
Oct. 23, 2014 · 10:29 a.m.
145 views
Gut microbial richness impacts human health
Dusko Ehrlich, INRA, Jouy-en-Josas, France
Oct. 23, 2014 · 11:07 a.m.
354 views
Q&A : Gut microbial richness impacts human health
Dusko Ehrlich, INRA, Jouy-en-Josas, France
Oct. 23, 2014 · 11:44 a.m.
Cross-talk between the mucosal immune system and environmental factors
Hiroshi Kiyono, The University of Tokyo, Japan
Oct. 23, 2014 · 11:56 a.m.
331 views
Q&A : Cross-talk between the mucosal immune system and environmental factors
Hiroshi Kiyono, The University of Tokyo, Japan
Oct. 23, 2014 · 12:31 p.m.
Introduction of the Session 2 : Host - Microbiome Interaction
Susan Suter, University of Geneva, Switzerland
Oct. 23, 2014 · 1:41 p.m.
143 views
Mechanisms of cross talk in the gut
Annick Mercenier, Nestlé Research Center, Lausanne, Switzerland
Oct. 23, 2014 · 1:55 p.m.
393 views
Q&A : Mechanisms of cross talk in the gut
Annick Mercenier, Nestlé Research Center, Lausanne, Switzerland
Oct. 23, 2014 · 2:34 p.m.
106 views
Relationship of diet to gut microbiota diversity, stability and health in older people
Paul O'Toole, University College Cork, Ireland
Oct. 23, 2014 · 3:52 p.m.
241 views
Q&A : Relationship of diet to gut microbiota diversity, stability and health in older people
Paul O'Toole, University College Cork, Ireland
Oct. 23, 2014 · 4:27 p.m.
Gut microbes and their role in malnutrition and obesity
Rob Knight, University of Colorado, Boulder, USA
Oct. 24, 2014 · 9:16 a.m.
1377 views
Q&A : Gut microbes and their role in malnutrition and obesity
Rob Knight, University of Colorado, Boulder, USA
Oct. 24, 2014 · 10:01 a.m.
The gut metagenome - your other genome
Jun Wang, BGI, Shenzhen, China
Oct. 24, 2014 · 10:19 a.m.
157 views
Q&A : The gut metagenome - your other genome
Jun Wang, BGI, Shenzhen, China
Oct. 24, 2014 · 10:53 a.m.
103 views
Fecal transplant to mine for novel probiotics
Max Nieuwdorp, Amsterdam Medical Center, The Netherlands
Oct. 24, 2014 · 11:04 a.m.
735 views
Q&A : Fecal transplant to mine for novel probiotics
Max Nieuwdorp, Amsterdam Medical Center, The Netherlands
Oct. 24, 2014 · 11:25 a.m.
Introduction of the Session 4 : Nutritional Interventions
Keiko Abe, The University of Tokyo, Japan
Oct. 24, 2014 · 12:46 p.m.
108 views
Interactions between gut microbiota, host genetics and diet
Liping Zhao, Jiao Tang University, Shanghai, China
Oct. 24, 2014 · 12:56 p.m.
465 views
Pediatric intervention - what works and what doesn't work
Hania Szajewska, The Medical University of Warsaw, Poland
Oct. 24, 2014 · 1:47 p.m.
265 views
Q&A : Pediatric intervention - what works and what doesn't work
Hania Szajewska, The Medical University of Warsaw, Poland
Oct. 24, 2014 · 2:15 p.m.
Perspectives for nutrition and the gut microbiome
Nicholas Schork, J. Craig Venter Institute, La Jolla, USA
Oct. 24, 2014 · 3:02 p.m.
1297 views
Q&A : Perspectives for nutrition and the gut microbiome
Nicholas Schork, J. Craig Venter Institute, La Jolla, USA
Oct. 24, 2014 · 3:46 p.m.

Recommended talks