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so I want to start with the first
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question and do you have explanation for
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the low incidence and sort of landfalls
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only on footsteps expect of the data
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historical data and no hope I would like
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but I don't we look at GBS of course
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that scene because it's the pattern
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where we have prevention strategies so
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compared the data to other countries and
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actually the proportion of GBS among
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episodes of the audience its is similar
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and Switzerland compared to other
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countries so we have a low incidence of
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audiences but it's not only do two Gs we
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also have a low incidence of e.coli
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early-onset sepsis so it's probably due
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to prenatal care i guess
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hi access to prenatal care might be an
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otherwise I don't have in idea may I
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give a comment to this just what could
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be hearings and don't you check we have
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four neonatology we have to apply the
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very strong definition of sepsis and
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some other papers and summarizing the
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incidence of steps in your nature not so
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strong definitions and these could be
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one point that we have a lower incidence
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because we have four more states
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election and the other thing is we are
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not pretty sure what is the coverage of
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of all the United sensations Richmond
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with these studies know so regarding the
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first comment other studies have
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included cases of meningitis with- got
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cultures but that would increase if we
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do if we would imagine that it would
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increase our numbers by around ten
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percent so that doesn't explain a a
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two-fold difference and of course we
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i mean the the 10 centers do not include
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all patients into two rounds of them
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could be a little by yourself
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Anita too so there are no guidelines
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went to do a lumbar puncture I mean
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there are no formal guidelines i mean in
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general in the literature people
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recommend to do well under pressure when
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blood cultures are positive when the
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patient is very sick which is very kind
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of vague and when the patient has
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neurologic symptoms
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yes how we did not record that in the
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study but this matches the literature
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neonatal sepsis in general is associated
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with a ten percent rate of meningitis
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but culture if you have many Jackie's a
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positive blood culture it's not in this
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what is interesting talk i have a
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question to the risk of mortality in the
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hospital acquired late-onset sepsis
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group you showed that the more premature
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baby is that the bigger risk of
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mortality and you also said countdown
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Ramona's have a big risk
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whatwhat to the other pathogens ok yeah
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so the domain killers in your study
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where stories and e.coli number one and
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staphylococcus sepsis in a study had
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twenty-five percent mortality so it was
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really a on top and about eighty percent
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of mortality was explained by stories
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ecoli coagulase-negative staphylococci
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and GPS so the first four and of course
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for candida and pseudomonas we cannot
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really see because they are so few cases
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so babies died premature babies because
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of a core class negative staphylococcal
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infection where the this would not
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really the in agreement with the
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literature because previous studies have
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shown that girl has negative
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staphylococci is not associated with
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increased mortality but with brain
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damage for study i would have to I mean
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this is ongoing analyzes so we would
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have to look at that because we recorded
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total deaths but we also recorded death
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related to sepsis so that's ongoing
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analyzes Eric thank you very very much
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for this interesting topic and I think
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there will be plenty of questions during
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the lunch meeting
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I think we have to finish the session we
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will have a very short business meeting
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that is exclusively for the members of