New diagnostic and therapeutic possibilities in perinatal medicine pose new challenges for obstetricians and neonatologists. Daily business has become more complex and highly sophisticated. 2019 Annual Conference of the Swiss Society of Neonatology (SSN) in Aarau, was held together with the Academy for Fetal and Maternal Medicine (AFMM) of the Swiss Society of Gynecology and Obstetrics. As a perinatal team, we face these new challenges and discuss them with experts in the field.